Sex hormones


Sex hormones are steroid hormones that are mainly produced by the testes or the ovaries. Sex hormones are responsible for controlling reproductive function and sexual development. Estrogens and progestins are female sex hormones and androgens are male sex hormones.

See also 5-alpha-reductase inhibitors androgens and anabolic steroids contraceptives estrogens gonadotropin releasing hormones gonadotropins hormone replacement therapy miscellaneous sex hormones progestins sex hormone combinations Drug List:
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Sexual Disorders Medications


Topics under Sexual Disorders Erectile Dysfunction (16 drugs) Hypersexuality State (0 drugs) Hypoactive Sexual Desire Disorder (0 drugs) Premature Ejaculation (1 drug)
Drug List:
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Sexually Transmitted Diseases Medications


Definition of Sexually Transmitted Diseases: Sexually transmitted diseases (STDs) are infections that you can get from having sex with someone who has the infection. The causes of STDs are bacteria, parasites and viruses.

Topics under Sexually Transmitted Diseases Chlamydia Infection (66 drugs in 3 topics) Gonococcal Infection (41 drugs in 3 topics) Herpes Simplex (34 drugs in 8 topics) HIV Infection (53 drugs) Human Papilloma Virus (17 drugs in 4 topics) Syphilis (94 drugs in 10 topics) Trichomoniasis (5 drugs) Learn more about Sexually Transmitted Diseases

Harvard Health Guide:

Symptoms and treatment for Sexually Transmitted Diseases
Drug List:
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Sex hormone combinations


A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Sex hormone combinations are products that contain more than one sex hormone, either estrogen and progestin or estrogen and androgen.

Estrogens are a group of hormones that are synthesized mainly by the ovaries and a small amount is synthesized by the testes in males and by the adrenal cortex in both sexes. The placenta produces a fairly large amount of estrogen as well. The three main endogenous estrogens are estradiol, estriol and estrone.

Progestins are a group of naturally occurring or synthetic steroid hormones. The naturally occurring progestin is progesterone, which is secreted by the corpus luteum of the ovary, the placenta and also (in small amounts) by the adrenal cortex and testes. It prepares the inner lining of the uterus for pregnancy, and if pregnancy occurs it maintains the uterus through the pregnancy and prevents ovulation by the ovaries during pregnancy.

Androgens are steroid hormones that stimulate development of male sex organs and sexual characteristics. Androgens are mainly released by the testes and small amounts are released by the adrenal cortex and ovaries.

The combinations, which have estrogen and progestin are used as birth control or to treat menopausal symptoms. Combinations with estrogen and androgen are used control menopausal symptoms.

See also

Medical conditions associated with sex hormone combinations:

Abnormal Uterine Bleeding Acne Atrophic Urethritis Atrophic Vaginitis Birth Control Endometriosis Gonadotropin Inhibition Hot Flashes Hypoestrogenism Menopausal Disorders Menstrual Disorders Oophorectomy Osteoporosis Polycystic Ovary Syndrome Postmenopausal Symptoms Prevention of Osteoporosis Primary Ovarian Failure Drug List: Estratest Junel-1-5-30 Norinyl-1-35 Zeosa Estratest-H-S Ortho-Novum-1-35 Angeliq Loestrin-1-20 Ovcon-35 Necon-1-35 Ortho-Novum-7-7-7 Activella Aranelle Gildess-Fe-1-5-0-03 Modicon Tri-Legest-Fe Junel-1-20 Femcon-Fe-Chewable-Tablets Lo-Loestrin-Fe Microgestin-1-20 Microgestin-Fe-1-5-30 Loestrin_24_Fe Climara_Pro Femhrt Junel-Fe-1-5-30 Junel-Fe-1-20 Microgestin-Fe-1-20 Prempro Necon-7-7-7 Briellyn Nortrel-7-7-7 Loestrin-Fe-1-20 Nortrel-1-35 Covaryx Loestrin-21-1-20 Balziva Brevicon Combipatch-Patch-Bi-Weekly Covaryx-Hs Cyclafem-1-35 Cyclafem-7-7-7 Eemt Eemt-Ds Eemt-Hs Essian Essian-H-S Estrostep-Fe Generess-Fe Genora-1-35 Gildess-Fe-1-0-2 Jenest Jevantique Jinteli Leena Loestrin-21-1-5-30 Loestrin-Fe-1-5-30 Lunelle Menogen Microgestin-1-5-30 Mimvey Necon-0-5-35 Necon-10-11 Nelova-0-5-35 Norethin-1-35-E Nortrel-0-5-35 Ovcon-35-Fe Ovcon-50 Prefest Premphase Syntest-Ds Syntest-Hs Tilia-Fe Tri-Legest Tri-Norinyl Zenchent Zenchent-Fe
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Vardenafil Orally Disintegrating Tablets


Pronunciation: var-DEN-a-fil
Generic Name: Vardenafil
Brand Name: Staxyn
Vardenafil Orally Disintegrating Tablets are used for:

Treating erectile dysfunction (ED). It may also be used for other conditions as determined by your doctor.

Vardenafil Orally Disintegrating Tablets are a phosphodiesterase type 5 (PDE5) inhibitor. It works by helping to increase blood flow into the penis during sexual stimulation. This helps you to achieve and maintain an erection.

Do NOT use Vardenafil Orally Disintegrating Tablets if: you are allergic to any ingredient in Vardenafil Orally Disintegrating Tablets you have been advised by your doctor to avoid sexual activity because of heart problems you have certain heart problems (eg, severe heart failure, unstable angina), low blood pressure, uncontrolled high blood pressure, moderate to severe liver problems, or severe kidney problems that require dialysis you have certain hereditary degenerative eye problems (eg, retinitis pigmentosa) or hereditary problems of fructose intolerance you have had a heart attack, stroke, or life-threatening irregular heartbeat within the past 6 months you have a history of a certain type of irregular heartbeat (eg, congenital QT prolongation) or you take certain antiarrhythmic medicines (eg, quinidine, procainamide, amiodarone, sotalol) you are taking a nitrate (eg, isosorbide, nitroglycerin) in any form (eg, capsule, ointment, patch, tablet) or nitroprusside you use certain recreational drugs called "poppers" (eg, amyl nitrate or nitrite, butyl nitrate or nitrite) you are taking certain azole antifungals (eg, ketoconazole, itraconazole), HIV protease inhibitors (eg, indinavir, ritonavir), or certain macrolide antibiotics (eg, clarithromycin, erythromycin) you take another PDE5 inhibitor (eg, sildenafil, tadalafil), another medicine that contains vardenafil, or any other medicine for ED (eg, alprostadil)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Vardenafil Orally Disintegrating Tablets:

Some medical conditions may interact with Vardenafil Orally Disintegrating Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have a deformed penis (eg, cavernosal fibrosis, Peyronie disease), blood cell problems (eg, leukemia, multiple myeloma, sickle cell anemia), or any other condition that may increase the risk of a prolonged erection (priapism) if you have a history of a prolonged (more than 4 hours) or painful erection (priapism) if you have a history of certain eye problems (eg, macular degeneration, optic neuropathy, retinitis pigmentosa, nonarteritic anterior ischemic optic neuropathy [NAION], sudden vision loss) or hearing problems (eg, ringing in the ears, decreased hearing, hearing loss) if you have a history of liver or kidney problems, dialysis, high or low blood pressure, ulcers, seizures, lung problems (eg, pulmonary veno-occlusive disease), bleeding problems, blood vessel problems, or heart problems (eg, angina, aortic stenosis, heart failure) if you have a history of a heart attack, a stroke, a certain type of irregular heartbeat (long QT syndrome), or a family history of long QT syndrome

Some MEDICINES MAY INTERACT with Vardenafil Orally Disintegrating Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

Certain antiarrhythmics (eg, amiodarone, procainamide, quinidine, sotalol) because the risk of irregular heartbeat may be increased Alpha-blockers (eg, doxazosin), medicines for high blood pressure, nitrates (eg, isosorbide, nitroglycerin), or nitroprusside because severe low blood pressure with dizziness, lightheadedness, and fainting may occur Azole antifungals (eg, itraconazole, ketoconazole ), HIV protease inhibitors (eg, indinavir, ritonavir), macrolide antibiotics (eg, clarithromycin, erythromycin), or telithromycin because they may increase the risk of Vardenafil Orally Disintegrating Tablets's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Vardenafil Orally Disintegrating Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Vardenafil Orally Disintegrating Tablets:

Use Vardenafil Orally Disintegrating Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with Vardenafil Orally Disintegrating Tablets. Talk to your pharmacist if you have questions about this information. Take Vardenafil Orally Disintegrating Tablets by mouth with or without food. Take Vardenafil Orally Disintegrating Tablets about 1 hour before sexual activity. Do not take Vardenafil Orally Disintegrating Tablets more often than once daily or as directed by your doctor. Be sure your hands are completely dry before you remove Vardenafil Orally Disintegrating Tablets from the blister. Take Vardenafil Orally Disintegrating Tablets immediately after you remove it from the blister. Do not store the removed tablet for future use. Do not crush or split Vardenafil Orally Disintegrating Tablets. Place Vardenafil Orally Disintegrating Tablets on the tongue. Allow it to completely dissolve. Take Vardenafil Orally Disintegrating Tablets without liquid. Do not eat grapefruit or drink grapefruit juice while you use Vardenafil Orally Disintegrating Tablets. If you miss a dose of Vardenafil Orally Disintegrating Tablets and you still intend to engage in sexual activity, take it as soon as you remember. Continue to take it as directed by your doctor.

Ask your health care provider any questions you may have about how to use Vardenafil Orally Disintegrating Tablets.

Important safety information: Vardenafil Orally Disintegrating Tablets may cause drowsiness, dizziness, fainting, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Vardenafil Orally Disintegrating Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. Vardenafil Orally Disintegrating Tablets may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects. Patients with heart problems who take Vardenafil Orally Disintegrating Tablets may be at increased risk of heart-related side effects, including a heart attack or stroke. Symptoms of a heart attack may include chest, shoulder, neck, or jaw pain; numbness of an arm or leg; severe dizziness, headache, nausea, stomach pain, or vomiting; fainting; or vision changes. Symptoms of a stroke may include confusion, vision or speech changes, one-sided weakness, or fainting. Contact your doctor or seek medical attention right away if you experience these symptoms. Do not switch between Vardenafil Orally Disintegrating Tablets and vardenafil tablets without checking with your doctor. The tablets may not provide the same amount of medicine to your body as the same dose of Vardenafil Orally Disintegrating Tablets. Discuss any questions or concerns with your doctor. Vardenafil Orally Disintegrating Tablets contains phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product. Vardenafil Orally Disintegrating Tablets may rarely cause a prolonged (more than 4 hours) or painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens. Vardenafil Orally Disintegrating Tablets does not stop the spread of HIV or other sexually transmitted diseases (STDs) to others through sexual contact. Use barrier methods of birth control (eg, condoms) if you have HIV infection or an STD. Vardenafil Orally Disintegrating Tablets will not prevent pregnancy. If your partner may become pregnant and you wish to avoid pregnancy, be sure to use an effective form of birth control. Vardenafil Orally Disintegrating Tablets may uncommonly cause mild, temporary vision changes (eg, blurred vision, sensitivity to light, blue/green color tint to vision). Contact your doctor if vision changes persist or are severe. Rarely, an eye problem called NAION has been reported in patients who took Vardenafil Orally Disintegrating Tablets. This may lead to decreased vision or permanent loss of vision in some cases. If you notice a sudden decrease in vision or loss of vision in one or both eyes, contact your doctor right away. Sudden decreases in hearing and loss of hearing have been reported in some patients who have taken Vardenafil Orally Disintegrating Tablets. Sometimes they also noticed ringing in the ears or dizziness. If you notice a sudden decrease or loss of hearing, contact your doctor right away. Do not use other medicines or treatments for ED while you are taking Vardenafil Orally Disintegrating Tablets without first checking with your doctor. Tell your doctor or dentist that you take Vardenafil Orally Disintegrating Tablets before you receive any medical or dental care, emergency care, or surgery (including care for a heart problem). Use Vardenafil Orally Disintegrating Tablets with caution in the ELDERLY; they may be more sensitive to its effects, including NAION. Vardenafil Orally Disintegrating Tablets are not recommended for use in CHILDREN; safety and effectiveness in children have not been confirmed. PREGNANCY and BREAST-FEEDING: Vardenafil Orally Disintegrating Tablets are not approved for use in women. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Vardenafil Orally Disintegrating Tablets while you are pregnant. It is not known if Vardenafil Orally Disintegrating Tablets are found in breast milk. If you are or will be breast-feeding while you use Vardenafil Orally Disintegrating Tablets, check with your doctor. Discuss any possible risks to your baby. Possible side effects of Vardenafil Orally Disintegrating Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; flushing; headache; heartburn; mild back pain; stuffy nose; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest, jaw, or left arm pain; fainting; fast, slow, or irregular heartbeat; memory loss; numbness of an arm or leg; prolonged, painful erection; ringing in the ears; seizures; severe back or muscle pain; severe or persistent dizziness; severe or persistent vision changes; sudden decrease or loss of hearing; sudden decrease or loss of vision in one or both eyes; sudden, severe headache or vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Vardenafil side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include chest pain; fainting; prolonged erection; severe back or muscle pain; severe dizziness; severe or persistent vision changes.

Proper storage of Vardenafil Orally Disintegrating Tablets:

Store Vardenafil Orally Disintegrating Tablets at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store in the original packaging away from heat, moisture, and light. Do not store in the bathroom. Do not use if the blister is open, torn, or broken. Keep Vardenafil Orally Disintegrating Tablets out of the reach of children and away from pets.

General information: If you have any questions about Vardenafil Orally Disintegrating Tablets, please talk with your doctor, pharmacist, or other health care provider. Vardenafil Orally Disintegrating Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Vardenafil Orally Disintegrating Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Vardenafil resources Vardenafil Side Effects (in more detail) Vardenafil Use in Pregnancy & Breastfeeding Vardenafil Drug Interactions Vardenafil Support Group 45 Reviews for Vardenafil - Add your own review/rating Compare Vardenafil with other medications Erectile Dysfunction
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fulvestrant Intramuscular


ful-VES-trant

Commonly used brand name(s)

In the U.S.

Faslodex

Available Dosage Forms:

Solution

Therapeutic Class: Antiestrogen

Uses For fulvestrant

Fulvestrant injection is used to treat metastatic breast cancer (cancer that has spread) that is hormone-receptor positive in women who have already stopped menstruating (postmenopausal). It is used for women who have breast cancer that has not improved after using other cancer medicines.

Many of the breast cancer tumors will grow when estrogen is available in the body. fulvestrant blocks the effects of the estrogen hormone in the body. As a result, the amount of estrogen that the tumor is exposed to is reduced, which will limit the growth of the tumor.

fulvestrant is available only with your doctor's prescription.

Before Using fulvestrant

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For fulvestrant, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to fulvestrant or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of fulvestrant injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of fulvestrant injection in the elderly.

Pregnancy Pregnancy Category Explanation All Trimesters D Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk. Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of fulvestrant. Make sure you tell your doctor if you have any other medical problems, especially:

Bleeding problems or Thrombocytopenia (low platelets in the blood)—Use with caution. May make these conditions worse. Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body. Proper Use of fulvestrant

Medicines used to treat cancer are very strong and can have many side effects. Before receiving fulvestrant, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

You will receive fulvestrant while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you fulvestrant. fulvestrant is given as a shot into one of your buttocks muscles.

Fulvestrant injection comes with patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Missed Dose

fulvestrant needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Precautions While Using fulvestrant

It is very important that your doctor check your progress at regular visits to make sure that the medicine is working properly. Blood tests may be needed to check for unwanted effects.

It is unlikely that a postmenopausal woman may become pregnant. But, you should know that using fulvestrant while you are pregnant could harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while receiving the medicine, tell your doctor right away.

fulvestrant may cause you to have bleeding from the vagina, especially when you first start using it. If the bleeding continues or is bothersome, check with your doctor right away.

Cancer medicines can cause nausea or vomiting, even after receiving medicines to prevent it. If you have nausea and vomiting after receiving fulvestrant, talk to your doctor or nurse about ways to control these effects.

fulvestrant Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common Bloating or swelling of the face, arms, hands, lower legs, or feet rapid weight gain tingling of the hands or feet unusual weight gain or loss Less common Difficult or labored breathing shortness of breath tightness in the chest wheezing Incidence not known Black, tarry stools chest pain chills cough fever flushing or redness of the skin hives or welts itching large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs pain in the chest, groin, or legs, especially the calves painful or difficult urination severe and sudden headache skin rash slurred speech sore throat sores, ulcers, or white spots on the lips or in the mouth sudden loss of coordination sudden and severe weakness or numbness in the arm or leg sudden unexplained shortness of breath swollen glands unusual bleeding or bruising unusual tiredness or weakness vaginal bleeding vision changes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common Back pain bladder pain bloody or cloudy urine body aches or pain bone pain burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings depression diarrhea difficulty having a bowel movement (stool) difficulty with moving dizziness dryness or soreness of the throat feeling faint, dizzy, or lightheaded feeling of warmth or heat feeling sad or empty frequent urge to urinate general feeling of discomfort or illness headache hoarseness irritability joint pain lack or loss of appetite lack or loss of strength loss of interest or pleasure lower back or side pain muscle aches and pains muscle stiffness nausea pain at the injection site pain in the arms or legs pelvic pain shivering skin rash stomach pain sudden sweating tender, swollen glands in the neck trouble concentrating trouble with swallowing unable to sleep voice changes vomiting weight loss Less common Nervousness pain, swelling, or redness in the joints pale skin Incidence not known Dizziness or lightheadedness feeling of constant movement of self or surroundings sensation of spinning

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: fulvestrant Intramuscular side effects (in more detail)

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The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More fulvestrant Intramuscular resources Fulvestrant Intramuscular Side Effects (in more detail) Fulvestrant Intramuscular Use in Pregnancy & Breastfeeding Fulvestrant Intramuscular Support Group 3 Reviews for Fulvestrant Intramuscular - Add your own review/rating Compare fulvestrant Intramuscular with other medications Breast Cancer Breast Cancer, Metastatic
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Ex-Lax Senna


1. Name Of The Medicinal Product

Ex-Lax® Senna

2. Qualitative And Quantitative Composition

Each tablet contains 15 mg of sennosides

For Excipients, see section 6.1

3. Pharmaceutical Form

Chocolate bar of tablet

4. Clinical Particulars 4.1 Therapeutic Indications

Relief of occasional constipation

4.2 Posology And Method Of Administration

The following doses are normally taken at bedtime

Adults: 1 tablet

Children 6 and over: ? tablet

Not recommended for children under 6.

There is no indication that the dosage should be modified for the elderly.

Route: Oral route of administration

4.3 Contraindications

Ex-Lax Senna should not be used when intestinal obstruction, bleeding or persistent abdominal symptoms are present.

Not recommended in cases of ileostomy or colostomy.

4.4 Special Warnings And Precautions For Use

Prolonged use is not recommended. Ex-Lax Senna should not be used for more than 7 days without seeking medical advice.

Label/leaflet precaution:

 

If a laxative is needed every day or there is persistent abdominal pain - consult your doctor.

If there is no bowel movement after 3 days consult your doctor.

Ex-Lax Senna should be used with caution shortly after bowel surgery.

During use of Ex-Lax Senna, an adequate level of fluid intake should be maintained

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

None stated.

4.6 Pregnancy And Lactation

No known adverse effects during pregnancy.

Clinical studies have shown that the breast fed infants mothers taking a senna laxative did not show any side effects to the drug

4.7 Effects On Ability To Drive And Use Machines

None known.

4.8 Undesirable Effects

Temporary mild griping may occur.

4.9 Overdose

Overdosage may result in diarrhoea with excessive loss of water and electrolytes, particularly potassium. Treatment should include an increase in fluid intake to reverse the loss of fluid and electrolytes. Prolong, excessive use of laxatives without interruption should be avoided because of the risk of electrolyte imbalance and in extreme cases the possibility of irreversible adverse effects on the bowel.

5. Pharmacological Properties 5.1 Pharmacodynamic Properties

Senna is an anthraquinone laxative which is used to treat constipation and for bowel evacuation before radiological procedures. The active anthraquinones are liberated into the colon from the glycosides by colonic bacteria and an effect usually occurs 6 to 12 hours after administration.

5.2 Pharmacokinetic Properties

There is some absorption of the anthraquinones from senna preparations following hydrolysis by colonic bacteria. Excretion occurs in the urine and the faeces and also in other secretions including milk.

(Although anthraquinone derivatives may be excreted in the milk of lactating mothers, following normal dosage the concentration is usually insufficient to affect the nursing infant)

5.3 Preclinical Safety Data

Not applicable.

6. Pharmaceutical Particulars 6.1 List Of Excipients

Confectionery chocolate comprising:

Cocoa liquor

Sucrose

Cocoa butter

Lecithin

Vanilin

6.2 Incompatibilities

None known

6.3 Shelf Life

60 months

6.4 Special Precautions For Storage

Do not store above 25°C

6.5 Nature And Contents Of Container

Bars of 6, 9 and 12 tablets wrapped in paper backed aluminium foil, or aluminium foil, and packed into cartons.

Pack sizes: 6, 9, 12, 18, 24, 36 or 48 tablets.

6.6 Special Precautions For Disposal And Other Handling

Not applicable

7. Marketing Authorisation Holder

Novartis Consumer Health UK Ltd.

Wimblehurst Road

Horsham

West Sussex

RH12 5AB

United Kingdom

Trading as Novartis Consumer Health

8. Marketing Authorisation Number(S)

PL 00030/0131

9. Date Of First Authorisation/Renewal Of The Authorisation

01 July 1997

10. Date Of Revision Of The Text

15 December 2006

Legal category: GSL


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Inderal Intravenous


Generic Name: propranolol (Intravenous route)

proe-PRAN-oh-lol

Commonly used brand name(s)

In the U.S.

Inderal

Available Dosage Forms:

Solution

Therapeutic Class: Cardiovascular Agent

Pharmacologic Class: Beta-Adrenergic Blocker, Nonselective

Uses For Inderal

Propranolol injection is used to control fast heartbeats and abnormal heart rhythms .

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and at a regular rhythm .

This medicine is available only with your doctor's prescription .

Before Using Inderal

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of propranolol injection in the pediatric population. Safety and efficacy have not been established .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of propranolol injection in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require an adjustment of dosage in patients receiving propranolol injection .

Pregnancy Pregnancy Category Explanation All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Thioridazine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Albuterol Amiodarone Arformoterol Bambuterol Bitolterol Broxaterol Bupivacaine Clenbuterol Clonidine Colterol Diatrizoate Diltiazem Dronedarone Epinephrine Fenoldopam Fenoterol Formoterol Haloperidol Hexoprenaline Indacaterol Isoetharine Levalbuterol Lidocaine Mefloquine Mepivacaine Metaproterenol Pirbuterol Prilocaine Procaterol Reproterol Rimiterol Ritodrine Salmeterol Terbutaline Tretoquinol Tulobuterol Verapamil

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acarbose Aceclofenac Acemetacin Acetohexamide Alclofenac Alfuzosin Amlodipine Apazone Arbutamine Benfluorex Benoxaprofen Bromfenac Bufexamac Bunazosin Carprofen Chlorpromazine Chlorpropamide Cimetidine Clometacin Clonixin Dexketoprofen Diclofenac Diflunisal Digoxin Dihydroergotamine Dipyrone Disopyramide Doxazosin Droxicam Ergotamine Etodolac Etofenamate Felbinac Felodipine Fenbufen Fenoprofen Fentiazac Flecainide Floctafenine Flufenamic Acid Flurbiprofen Fluvoxamine Gliclazide Glimepiride Glipizide Gliquidone Glyburide Guar Gum Guggul Ibuprofen Indomethacin Indoprofen Insulin Insulin Aspart, Recombinant Insulin Glulisine Insulin Lispro, Recombinant Isoxicam Ketoprofen Ketorolac Lacidipine Lercanidipine Lornoxicam Manidipine Meclofenamate Mefenamic Acid Meloxicam Metformin Mibefradil Miglitol Moxisylyte Nabumetone Naproxen Nicardipine Nifedipine Niflumic Acid Nilvadipine Nimesulide Nimodipine Nisoldipine Nitrendipine Oxaprozin Oxyphenbutazone Phenoxybenzamine Phentolamine Phenylbutazone Phenylephrine Piperine Pirazolac Piroxicam Pirprofen Pranidipine Prazosin Propoxyphene Propyphenazone Proquazone Quinidine Repaglinide Rifapentine Rizatriptan Sertraline St John's Wort Sulindac Suprofen Tamsulosin Tenidap Tenoxicam Terazosin Tiaprofenic Acid Tolazamide Tolbutamide Tolmetin Trimazosin Troglitazone Tubocurarine Urapidil Zileuton Zomepirac Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

Angina (severe chest pain)—May provoke chest pain if stopped too quickly . Asthma or Bradycardia (slow heartbeat) or Heart block or Heart failure—Should not use in patients with these conditions . Diabetes or Hyperthyroidism (overactive thyroid) or Hypoglycemia (low blood sugar)—May cover up some of the signs and symptoms of these diseases, such as a fast heartbeat . Kidney disease or Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body . Lung disease (e.g., bronchitis, emphysema)—May cause difficulty with breathing in patients with this condition . Wolff-Parkinson-White syndrome (rare heart condition)—May cause a very slow heartbeat in patients with this condition . Proper Use of Inderal

A nurse or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins .

Precautions While Using Inderal

Your doctor will only give you a few doses of this medicine until your condition improves, and then you will be switched to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor .

Inderal Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common Blurred vision chest pain or discomfort confusion decreased urine output dilated neck veins dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly extreme fatigue irregular breathing lightheadedness, dizziness, or fainting shortness of breath slow or irregular heartbeat sweating swelling of face, fingers, feet, or lower legs tightness in chest troubled breathing unusual tiredness or weakness weight gain wheezing Rare Blisters, hives, or itching fever and chills general feeling of discomfort or illness hair loss headaches muscle or joint pain skin rash sore throat swollen glands Incidence not determined Abdominal pain, usually after eating a meal abdominal tenderness black, tarry stools blood in urine bloody nose bloody stools body aches or pain burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings congestion constipation cough decreased awareness or responsiveness diarrhea difficult or labored breathing dryness or soreness of throat general feeling of tiredness or weakness heavier menstrual periods hoarseness lower back or side pain mimicry of speech or movements mutism nausea negativism no blood pressure or pulse noisy breathing painful or difficult urination paleness or cold feeling in fingertips and toes peculiar postures or movements, mannerisms, or grimacing pinpoint red or purple spots on skin rectal bleeding reddened skin runny nose severe sleepiness sores on the skin sores, ulcers, or white spots on lips or in mouth stopping of heart tender, swollen glands in neck tingling or pain in fingers or toes when exposed to cold trouble in swallowing unconsciousness unusual bleeding or bruising voice changes vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare Decreased interest in sexual intercourse dry eyes inability to have or keep an erection loss in sexual ability, desire, drive, or performance pain of penis on erection skin irritation or rash, including rash that looks like psoriasis thinning of hair Incidence not determined Confusion about identity, place, and time crying depersonalization disturbed color perception double vision dysphoria euphoria halos around lights loss of strength or energy loss of vision mental depression muscle weakness night blindness overbright appearance of lights paranoia quick to react or overreact emotionally rapidly changing moods seeing, hearing, or feeling things that are not there short-term memory loss sleeplessness trouble sleeping tunnel vision unable to sleep unusual drowsiness, dullness, or feeling of sluggishness vivid dreams

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Inderal Intravenous side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Inderal Intravenous resources Inderal Intravenous Side Effects (in more detail) Inderal Intravenous Use in Pregnancy & Breastfeeding Drug Images Inderal Intravenous Drug Interactions Inderal Intravenous Support Group 32 Reviews for Inderal Intravenous - Add your own review/rating Compare Inderal Intravenous with other medications Angina Aortic Stenosis Arrhythmia Benign Essential Tremor Heart Attack Hemangioma High Blood Pressure Migraine Prevention Mitral Valve Prolapse Performance Anxiety Pheochromocytoma Thyrotoxicosis
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Polocaine-MPF


Generic Name: mepivacaine (me PIV a kane)
Brand Names: Carbocaine, Carbocaine HCl, Polocaine, Polocaine-MPF

What is Polocaine-MPF (mepivacaine)?

Mepivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.

Mepivacaine is used as a local (in only one area) anesthetic for an epidural or spinal block. It is also used as an anesthetic for dental procedures.

Mepivacaine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Polocaine-MPF (mepivacaine)? You should not receive mepivacaine if you have ever had an allergic reaction to any type of numbing medicine.

Before receiving this medication, tell your doctor if you have liver disease, kidney disease, high or low blood pressure, asthma or a sulfite allergy, a history of heart disease or stroke, heart block or coronary artery disease, a heart rhythm disorder, or a thyroid disorder.

This medication can cause numbness for an extended period of time. Avoid eating, chewing gum, or drinking hot liquids until the feeling in your mouth has returned completely. Chewing while your mouth is numb could result in a bite injury to your tongue, lips, or inside of your cheek.

Spinal numbing medications can have long-lasting or permanent effects on certain body processes such as sexual function, bowel or bladder control, and movement or feeling in your legs or feet. Talk with your doctor about your specific risk of nerve damage from mepivacaine. What should I discuss with my health care provider before receiving Polocaine-MPF (mepivacaine)? You should not receive mepivacaine if you have ever had an allergic reaction to any type of numbing medicine.

Before receiving mepivacaine, tell your doctor if you are allergic to any drugs, or if you have:

liver disease; kidney disease;

low or high blood pressure;

asthma or a sulfite allergy;

a history of heart disease or stroke;

heart block or coronary artery disease;

a heart rhythm disorder; or

a thyroid disorder.

If you have any of these conditions, you may need a dose adjustment or special precautions to safely receive mepivacaine.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Before you receive mepivacaine, tell your doctor if you are pregnant. It is not known whether mepivacaine passes into breast or if it could harm a nursing baby. Before you receive mepivacaine, tell your doctor if you are breast-feeding a baby. How is mepivacaine given?

Mepivacaine is given as an injection placed into an area of your lower back near your spine. You will receive this injection in a hospital or surgical setting.

When used for a dental procedure, mepivacaine is given as an injection that is usually placed into the gum area inside your mouth. You will receive this injection in a dentist's office or oral surgical setting.

Spinal numbing medications can have long-lasting or permanent effects on certain body processes such as sexual function, bowel or bladder control, and movement or feeling in your legs or feet. Talk with your doctor about your specific risk of nerve damage from mepivacaine. Your breathing, blood pressure, oxygen levels, and other vital signs may be watched closely while you are receiving mepivacaine. What happens if I miss a dose?

Since mepivacaine is given as needed before a surgery or other medical procedure, you are not likely to be on a dosing schedule.

What happens if I overdose? Tell your caregivers right away if you think you have received too much of this medicine.

Overdose symptoms may include extreme drowsiness, fainting, seizure (convulsions), shallow breathing, or slow heart rate.

What should I avoid after receiving Polocaine-MPF (mepivacaine)?

This medication can cause numbness for an extended period of time. Avoid eating, chewing gum, or drinking hot liquids until the feeling in your mouth has returned completely. Chewing while your mouth is numb could result in a bite injury to your tongue, lips, or inside of your cheek.

Polocaine-MPF (mepivacaine) side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling or puffiness of your face, lips, tongue, or throat. Tell your caregivers at once if you have a serious side effect such as:

weak or shallow breathing;

feeling like you might pass out;

sweating, anxiety, confusion;

blurred vision, ringing in your ears;

numbness or tingling around your mouth;

slow heart rate, weak pulse;

metallic taste in your mouth;

tremors, muscle twitching; or

seizure (convulsions).

Less serious side effects may include:

nausea, vomiting;

nervousness;

dizziness; or

drowsiness.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Polocaine-MPF (mepivacaine)?

Before receiving mepivacaine, tell your doctor if you are using any of the following drugs:

cold medicine, diet pills, stimulants, or medication to treat ADHD;

medicine to treat a psychiatric disorder (Haldol, Inapsine, Thorazine, Prolixin, Serentil, Mellaril, and others);

medication to treat nausea and vomiting, such as Compazine or Motillium;

ergot medicine such as ergotamine (Ergomar, Cafergot), dihydroergotamine (D.H.E. 45, Migranal), ergonovine (Ergotrate), or methylergonovine (Methergine);

an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate); or

antidepressants such as amitriptyline (Elavil, Etrafon), desipramine (Norpramin), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), and others.

This list is not complete and there may be other drugs that can interact with mepivacaine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors.

More Polocaine-MPF resources Polocaine-MPF Use in Pregnancy & Breastfeeding Polocaine-MPF Drug Interactions Polocaine-MPF Support Group 0 Reviews for Polocaine-MPF - Add your own review/rating Mepivacaine Prescribing Information (FDA) Carbocaine Prescribing Information (FDA) Carbocaine MedFacts Consumer Leaflet (Wolters Kluwer) Compare Polocaine-MPF with other medications Local Anesthesia Where can I get more information? Your doctor or pharmacist can provide more information about mepivacaine.
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timolol


Generic Name: timolol (TIH mo lol)
Brand Names: Blocadren

What is timolol?

Timolol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Timolol is used to treat hypertension (high blood pressure).

Timolol may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about timolol? Do not stop taking timolol without first talking to your doctor. Stopping suddenly may make your condition worse.

If you need to have any type of surgery, you may need to temporarily stop using timolol. Be sure the surgeon knows ahead of time that you are using timolol.

Timolol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking timolol.

Timolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.

What should I discuss with my healthcare provider before taking timolol?

Before taking timolol, tell your doctor if you have:

asthma, bronchitis, emphysema;

diabetes;

low blood pressure;

a heart problem such as heart block, sick sinus syndrome, slow heart rate, or congestive heart failure;

depression;

liver or kidney disease;

a thyroid disorder;

myasthenia gravis;

pheochromocytoma; or

problems with circulation (such as Raynaud's syndrome).

If you have any of these conditions, you may not be able to use timolol, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Timolol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. How should I take timolol?

Take timolol exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor.

Take this medication with a full glass of water.

Take timolol at the same time every day.

Do not skip doses or stop taking timolol without first talking to your doctor. Stopping suddenly may make your condition worse.

To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. It is important that you not miss any scheduled visits to your doctor.

If you need to have any type of surgery, tell the surgeon that you are using timolol. You may need to briefly stop using timolol before having surgery.

Timolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.

Store timolol at room temperature away from moisture and heat.

See also: Timolol dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. If your next dose is less than 8 hours away, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose? Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a timolol overdose may include uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, or seizure (convulsions).

What should I avoid while taking timolol? Timolol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking timolol. Timolol side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

slow or uneven heartbeats;

feeling light-headed, fainting;

feeling short of breath, even with mild exertion;

swelling of your ankles or feet;

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

depression; or

cold feeling in your hands and feet.

Other less serious side effects are more likely to occur, such as:

decreased sex drive, impotence, or difficulty having an orgasm;

sleep problems (insomnia);

tired feeling; or

anxiety, nervousness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Timolol Dosing Information

Usual Adult Dose for Hypertension:

Initial dose: 10 mg orally twice a day.
Maintenance dose: 10-20 mg orally twice a day.

Usual Adult Dose for Angina Pectoris:

Initial dose: 10 mg orally twice a day.
Maintenance dose: 10-20 mg orally twice a day.

Usual Adult Dose for Myocardial Infarction:

Initial dose: 10 mg orally twice a day.

Usual Adult Dose for Migraine Prophylaxis:

Initial dose: 10 mg orally twice a day.
Maintenance dose: 10-30 mg given in 1-2 divided doses.

What other drugs will affect timolol?

Before taking timolol, tell your doctor if you are using:

allergy treatments (or if you are undergoing allergy skin-testing);

clonidine (Catapres);

guanabenz (Wytensin);

an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam);

a diabetes medication such as insulin, glyburide (Diabeta, Micronase, Glynase), glipizide (Glucotrol), chlorpropamide (Diabinese), or metformin (Glucophage);

a heart medication such as nifedipine (Procardia, Adalat), reserpine (Serpasil), verapamil (Calan, Verelan, Isoptin), diltiazem (Cartia, Cardizem);

medicine for asthma or other breathing disorders, such as albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), terbutaline (Brethaire, Brethine, Bricanyl), and theophylline (Theo-Dur, Theolair); or

cold medicines, stimulant medicines, or diet pills.

If you are using any of these drugs, you may not be able to take timolol, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect timolol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More timolol resources Timolol Dosage Timolol Use in Pregnancy & Breastfeeding Drug Images Timolol Drug Interactions Timolol Support Group 0 Reviews for Timolol - Add your own review/rating timolol Advanced Consumer (Micromedex) - Includes Dosage Information Timolol Prescribing Information (FDA) Timolol eent Monograph (AHFS DI) Timolol MedFacts Consumer Leaflet (Wolters Kluwer) Blocadren Prescribing Information (FDA) Timolol Maleate Monograph (AHFS DI) Compare timolol with other medications Angina Heart Attack High Blood Pressure Migraine Prevention Where can I get more information? Your pharmacist has additional information about timolol written for health professionals that you may read.
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